| Adrenergic α2C-receptors modulate the acoustic startle reflex, prepulse inhibition, and aggression in mice J Sallinen, A Haapalinna, T Viitamaa, BK Kobilka, M Scheinin Journal of Neuroscience 18 (8), 3035-3042, 1998 | 251 | 1998 |
| Neuroprotective effects of dexmedetomidine in the gerbil hippocampus after transient global ischemia J Kuhmonen, J Pokorny, R Miettinen, A Haapalinna, J Jolkkonen, ... The Journal of the American Society of Anesthesiologists 87 (2), 371-377, 1997 | 216 | 1997 |
| Genetic alteration of α2C-adrenoceptor expression in mice: influence on locomotor, hypothermic, and neurochemical effects of dexmedetomidine, a subtype-nonselective α2 … J Sallinen, RE Link, A Haapalinna, T Viitamaa, M Kulatunga, B Sjöholm, ... Molecular pharmacology 51 (1), 36-46, 1997 | 216 | 1997 |
| Neuroprotection by the α2-adrenoceptor agonist, dexmedetomidine, in rat focal cerebral ischemia J Jolkkonen, K Puurunen, J Koistinaho, R Kauppinen, A Haapalinna, ... European journal of pharmacology 372 (1), 31-36, 1999 | 179 | 1999 |
| Genetic alteration of the α2-adrenoceptor subtype c in mice affects the development of behavioral despair and stress-induced increases in plasma corticosterone levels J Sallinen, A Haapalinna, E MacDonald, T Viitamaa, J Lähdesmäki, ... Molecular psychiatry 4 (5), 443-452, 1999 | 141 | 1999 |
| Behavioral effects of the α2-adrenoceptor antagonist, atipamezole, after focal cerebral ischemia in rats J Jolkkonen, K Puurunen, S Rantakömi, A Härkönen, A Haapalinna, ... European journal of pharmacology 400 (2-3), 211-219, 2000 | 138 | 2000 |
| Pharmacological Properties, Central Nervous System Effects, and Potential Therapeutic Applications of Atipamezole, a Selective α2‐Adrenoceptor Antagonist A Pertovaara, A Haapalinna, J Sirviö, R Virtanen CNS drug reviews 11 (3), 273-288, 2005 | 137 | 2005 |
| Evaluation of the α2C-adrenoceptor as a neuropsychiatric drug target: studies in transgenic mouse models M Scheinin, J Sallinen, A Haapalinna Life sciences 68 (19-20), 2277-2285, 2001 | 132 | 2001 |
| An α2-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats K Puurunen, J Jolkkonen, J Sirviö, A Haapalinna, J Sivenius Neuropharmacology 40 (4), 597-606, 2001 | 129 | 2001 |
| Pharmacological characterization and CNS effects of a novel highly selective α2C‐adrenoceptor antagonist JP‐1302 J Sallinen, I Höglund, M Engström, J Lehtimäki, R Virtanen, J Sirviö, ... British journal of pharmacology 150 (4), 391-402, 2007 | 111 | 2007 |
| Evaluation of the effects of a specific α2-adrenoceptor antagonist, atipamezole, on α1-and α2-adrenoceptor subtype binding, brain neurochemistry and behaviour in comparison … A Haapalinna, T Viitamaa, E MacDonald, JM Savola, L Tuomisto, ... Naunyn-Schmiedeberg's archives of pharmacology 356, 570-582, 1997 | 99 | 1997 |
| Effects of dexmedetomidine after transient and permanent occlusion of the middle cerebral artery in the rat J Kuhmonen, A Haapalinna, J Sivenius Journal of neural transmission 108, 261-271, 2001 | 89 | 2001 |
| D-amphetamine and L-5-hydroxytryptophan-induced behaviours in mice with genetically-altered expression of the α2C-adrenergic receptor subtype J Sallinen, A Haapalinna, T Viitamaa, BK Kobilka, M Scheinin Neuroscience 86 (3), 959-965, 1998 | 89 | 1998 |
| Catechol 0-methyltransferase inhibitor tolcapone has minor influence on performance in experimental memory models in rats R Liljequist, A Haapalinna, M Ahlander, YH Li, PT Männistö Behavioural brain research 82 (2), 195-202, 1997 | 81 | 1997 |
| Selegiline combined with enriched-environment housing attenuates spatial learning deficits following focal cerebral ischemia in rats K Puurunen, J Jolkkonen, J Sirviö, A Haapalinna, J Sivenius Experimental neurology 167 (2), 348-355, 2001 | 71 | 2001 |
| Stimulation of alpha-1 adrenergic receptors facilitates spatial learning in rats T Puumala, S Greijus, K Narinen, A Haapalinna, P Riekkinen Sr, J Sirviö European neuropsychopharmacology 8 (1), 17-26, 1998 | 64 | 1998 |
| α‐Adrenoceptor‐Mediated Modulation of 5‐HT2 Receptor Agonist Induced Impulsive Responding in a 5‐Choice Serial Reaction Time Task T Koskinen, A Haapalinna, J Sirvi Pharmacology & toxicology 92 (5), 214-225, 2003 | 61 | 2003 |
| α2-Adrenergic control of dopamine overflow and metabolism in mouse striatum L Yavich, R Lappalainen, J Sirviö, A Haapalinna, E MacDonald European journal of pharmacology 339 (2-3), 113-119, 1997 | 60 | 1997 |
| Atipamezole, an α2-adrenoceptor antagonist, has disease modifying effects on epileptogenesis in rats A Pitkänen, S Narkilahti, Z Bezvenyuk, A Haapalinna, J Nissinen Epilepsy research 61 (1-3), 119-140, 2004 | 59 | 2004 |
| Dexmedetomidine reduces response tendency, but not accuracy of rats in attention and short-term memory tasks S Ruotsalainen, A Haapalinna, PJ Riekkinen SR, J Sirviö Pharmacology Biochemistry and Behavior 56 (1), 31-40, 1997 | 58 | 1997 |
