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Tim Kamerzell
Tim Kamerzell
The University of Kansas Medical Center
Подтвержден адрес электронной почты в домене kumc.edu
Название
Процитировано
Процитировано
Год
Protein–excipient interactions: Mechanisms and biophysical characterization applied to protein formulation development
TJ Kamerzell, R Esfandiary, SB Joshi, CR Middaugh, DB Volkin
Advanced drug delivery reviews 63 (13), 1118-1159, 2011
5402011
Coarse-grained modeling of the self-association of therapeutic monoclonal antibodies
A Chaudhri, IE Zarraga, TJ Kamerzell, JP Brandt, TW Patapoff, SJ Shire, ...
The Journal of Physical Chemistry B 116 (28), 8045-8057, 2012
1342012
The complex inter-relationships between protein flexibility and stability
TJ Kamerzell, CR Middaugh
Journal of pharmaceutical sciences 97 (9), 3494-3517, 2008
1342008
Increasing IgG concentration modulates the conformational heterogeneity and bonding network that influence solution properties
TJ Kamerzell, S Kanai, J Liu, SJ Shire, YJ Wang
The Journal of Physical Chemistry B 113 (17), 6109-6118, 2009
642009
Two-dimensional correlation spectroscopy reveals coupled immunoglobulin regions of differential flexibility that influence stability
TJ Kamerzell, CR Middaugh
Biochemistry 46 (34), 9762-9773, 2007
482007
Using empirical phase diagrams to understand the role of intramolecular dynamics in immunoglobulin G stability
JD Ramsey, ML Gill, TJ Kamerzell, ES Price, SB Joshi, SM Bishop, ...
Journal of pharmaceutical sciences 98 (7), 2432-2447, 2009
472009
Immunoglobulin dynamics, conformational fluctuations, and nonlinear elasticity and their effects on stability
TJ Kamerzell, JD Ramsey, CR Middaugh
The Journal of Physical Chemistry B 112 (10), 3240-3250, 2008
422008
The relative rate of immunoglobulin gamma 1 fragmentation
TJ Kamerzell, M Li, S Arora, JA Ji, YJ Wang
Journal of pharmaceutical sciences 100 (4), 1341-1349, 2011
322011
Characteristics of rhVEGF release from topical hydrogel formulations
JA Ji, J Liu, SJ Shire, TJ Kamerzell, S Hong, K Billeci, Y Shen, YJ Wang
Pharmaceutical research 27, 644-654, 2010
272010
Conformational flexibility, hydration and state parameter fluctuations of fibroblast growth factor-10: effects of ligand binding
TJ Kamerzell, JR Unruh, CK Johnson, CR Middaugh
Biochemistry 45 (51), 15288-15300, 2006
272006
Parathyroid hormone is a heparin/polyanion binding protein: binding energetics and structure modification
TJ Kamerzell, SB Joshi, D McClean, L Peplinskie, K Toney, D Papac, M Li, ...
Protein science 16 (6), 1193-1203, 2007
262007
The interaction of heparin/polyanions with bovine, porcine, and human growth hormone
SB Joshi, TJ Kamerzell, C McNown, CR Middaugh
Journal of pharmaceutical sciences 97 (4), 1368-1385, 2008
242008
Vibrational spectroscopy and chemometrics to characterize and quantitate trehalose crystallization
B Connolly, TW Patapoff, YJ Wang, JM Moore, TJ Kamerzell
Analytical biochemistry 399 (1), 48-57, 2010
212010
Prediction machines: applied machine learning for therapeutic protein design and development
TJ Kamerzell, CR Middaugh
Journal of Pharmaceutical Sciences 110 (2), 665-681, 2021
202021
Polar solvents decrease the viscosity of high concentration IgG1 solutions through hydrophobic solvation and interaction: formulation and biocompatibility considerations
TJ Kamerzell, AL Pace, M Li, DM Danilenko, M Mcdowell, YR Gokarn, ...
Journal of pharmaceutical sciences 102 (4), 1182-1193, 2013
202013
Spectroscopy and photophysics of indoline and indoline-2-carboxylic acid
MW Allen, JR Unruh, BD Slaughter, SJ Pyszczynski, TR Hellwig, ...
The Journal of Physical Chemistry A 107 (30), 5660-5669, 2003
182003
Thermodynamic and structural characterization of an antibody gel
O Esue, AX Xie, TJ Kamerzell, TW Patapoff
MAbs 5 (2), 323-334, 2013
122013
Concentrated polypeptide formulations with reduced viscosity
T Kamerzell, S Martin-Moe, YJ Wang
US Patent App. 13/388,962, 2013
52013
The structural basis of histone modifying enzyme specificity and promiscuity: Implications for metabolic regulation and drug design
TJ Kamerzell, B Mikell, L Chen, H Elias, B Dawn, C MacRae, ...
Advances in Protein Chemistry and Structural Biology 130, 189-243, 2022
12022
Coarse-grained modeling of antibody self-association
A Chaudhri, T Kamerzell, GA Voth
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010
12010
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Статьи 1–20