Scientific benchmarks for guiding macromolecular energy function improvement A Leaver-Fay, MJ O’Meara, M Tyka, R Jacak, Y Song, EH Kellogg, ... Methods in enzymology 523, 2013 | 245 | 2013 |
Dynamic interactions of proteins in complex networks: a more structured view A Stein, RA Pache, P Bernado, M Pons, P Aloy The FEBS journal 276 (19), 5390-5405, 2009 | 136 | 2009 |
Computational design of a modular protein sense-response system AA Glasgow, YM Huang, DJ Mandell, M Thompson, R Ritterson, ... Science 366 (6468), 1024-1028, 2019 | 108 | 2019 |
A web resource for standardized benchmark datasets, metrics, and Rosetta protocols for macromolecular modeling and design S ó Conchúir, KA Barlow, RA Pache, N Ollikainen, K Kundert, MJ O'Meara, ... PLOS one 10 (9), e0130433, 2015 | 87 | 2015 |
Uncovering new substrates for Aurora A kinase T Sardon, RA Pache, A Stein, H Molina, I Vernos, P Aloy EMBO reports 11 (12), 977-984, 2010 | 80 | 2010 |
The role of structural disorder in the rewiring of protein interactions through evolution R Mosca, RA Pache, P Aloy Molecular & Cellular Proteomics 11 (7), 2012 | 68 | 2012 |
Engineering a light-activated caspase-3 for precise ablation of neurons in vivo AD Smart, RA Pache, ND Thomsen, T Kortemme, GW Davis, JA Wells Proceedings of the National Academy of Sciences 114 (39), E8174-E8183, 2017 | 62 | 2017 |
A novel framework for the comparative analysis of biological networks RA Pache, P Aloy PloS one 7 (2), e31220, 2012 | 48 | 2012 |
NetAligner—a network alignment server to compare complexes, pathways and whole interactomes RA Pache, A Céol, P Aloy Nucleic acids research 40 (W1), W157-W161, 2012 | 45 | 2012 |
Towards a molecular characterisation of pathological pathways RA Pache, A Zanzoni, J Naval, JM Mas, P Aloy FEBS letters 582 (8), 1259-1265, 2008 | 42 | 2008 |
Incorporating high‐throughput proteomics experiments into structural biology pipelines: Identification of the low‐hanging fruits RA Pache, P Aloy Proteomics 8 (10), 1959-1964, 2008 | 15 | 2008 |
Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions RA Pache, MM Babu, P Aloy BMC Systems Biology 3, 1-18, 2009 | 14 | 2009 |
Systematic bioinformatics and experimental validation of yeast complexes reduces the rate of attrition during structural investigations MA Brooks, K Gewartowski, E Mitsiki, J Létoquart, RA Pache, Y Billier, ... Structure 18 (9), 1075-1082, 2010 | 10 | 2010 |
Accurate positioning of functional residues with robotics-inspired computational protein design C Krivacic, K Kundert, X Pan, RA Pache, L Liu, S O Conchúir, ... Proceedings of the National Academy of Sciences 119 (11), e2115480119, 2022 | 9 | 2022 |
Module walking using an SH3-like cell-wall-binding domain leads to a new GH184 family of muramidases OV Moroz, E Blagova, AA Lebedev, LK Skov, RA Pache, KM Schnorr, ... Acta Crystallographica Section D: Structural Biology 79 (8), 706-720, 2023 | 3 | 2023 |
Serine protease variants and polynucleotides encoding same K Ayabe, T Matsui, A Tomiki, Y Kurakata, EP Friis, JE Nielsen, RA Pache US Patent 10,927,361, 2021 | 3 | 2021 |
Xylanase variants and polynucleotides encoding same S Danielsen, PK Hansen, FW Rasmussen, RA Pache US Patent 10,208,301, 2019 | 2 | 2019 |
Stabilized endoglucanase variants SG Kaasgaard, FW Rasmussen, RA Pache, L Anderson, MLD Overgaard, ... US Patent 11,661,592, 2023 | 1 | 2023 |
Serine protease variants and polynucleotides encoding same K Ayabe, T Matsui, A Tomiki, Y Kurakata, EP Friis, JE Nielsen, RA Pache US Patent 11,447,763, 2022 | 1 | 2022 |
Increasing the precision of orthology-based complex prediction through network alignment RA Pache, P Aloy PeerJ 2, e413, 2014 | 1 | 2014 |