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Matthew A. Clarke
Matthew A. Clarke
Post-Doctoral Research Fellow, University College London
Verified email at ucl.ac.uk - Homepage
Title
Cited by
Cited by
Year
Executable cancer models: successes and challenges
MA Clarke, J Fisher
Nature Reviews Cancer 20 (6), 343-354, 2020
472020
Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling
P Kreuzaler, MA Clarke, EJ Brown, CH Wilson, RM Kortlever, N Piterman, ...
Proceedings of the National Academy of Sciences 116 (44), 22399-22408, 2019
182019
Using State Space Exploration to Determine How Gene Regulatory Networks Constrain Mutation Order in Cancer Evolution
MA Clarke, S Woodhouse, N Piterman, BA Hall, J Fisher
Automated Reasoning for Systems Biology and Medicine, 133-153, 2019
92019
HOXA9 has the hallmarks of a biological switch with implications in blood cancers
L Talarmain, MA Clarke, D Shorthouse, L Cabrera-Cosme, DG Kent, ...
Nature Communications 13 (1), 5829, 2022
62022
Executable network of SARS-CoV-2-host interaction predicts drug combination treatments
R Howell, MA Clarke, AK Reuschl, T Chen, S Abbott-Imboden, M Singer, ...
npj Digital Medicine 5 (1), 1-13, 2022
52022
Localized immune surveillance of primary melanoma in the skin deciphered through executable modeling
R Howell, J Davies, MA Clarke, A Appios, I Mesquita, Y Jayal, ...
Science Advances 9 (15), eadd1992, 2023
32023
Prognostic hallmarks in AML
MA Clarke, J Fisher
Nature Biomedical Engineering 3 (11), 847-849, 2019
12019
HOXA9 acts as a regulatory switch in acute myeloid leukaemia and myeloproliferative neoplasms
L Talarmain, MA Clarke, D Shorthouse, J Fisher, BA Hall
bioRxiv, 2021.03. 05.434116, 2021
2021
Executable Network of SARS-CoV-2-Host Interaction Predicts Drug Combination Treatments (preprint)
R Howell, MA Clarke, AK Reuschl, T Chen, S Abott-Imboden, M Singer, ...
2021
Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling
N Piterman, P Kreuzaler, MA Clarke, EJ Brown, CH Wilson, RM Kortlever, ...
University of Leicester, 2019
2019
Predictive Computational Modelling of the c-myc Gene Regulatory Network for Combinatorial Treatments of Breast Cancer
MA Clarke
2018
1 Obligatory tumour heterogeneity driven by Myc overexpression: mechanistic insights and therapeutic strategies
P Kreuzaler, M Clarke, E Brown, C Wilson, J Fisher, G Evan
ESMO Open 3, A1, 2018
2018
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Articles 1–12