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James Rosinski
James Rosinski
CHDI Management
Verified email at chdifoundation.org
Title
Cited by
Cited by
Year
Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy
C Tovar, J Rosinski, Z Filipovic, B Higgins, K Kolinsky, H Hilton, X Zhao, ...
Proceedings of the National Academy of Sciences 103 (6), 1888-1893, 2006
8092006
Integrated genomics and proteomics define huntingtin CAG length–dependent networks in mice
P Langfelder, JP Cantle, D Chatzopoulou, N Wang, F Gao, I Al-Ramahi, ...
Nature neuroscience 19 (4), 623-633, 2016
3632016
Molecular evolution of the Myb family of transcription factors: evidence for polyphyletic origin
JA Rosinski, WR Atchley
Journal of Molecular Evolution 46, 74-83, 1998
3591998
Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels
S Horvath, P Langfelder, S Kwak, J Aaronson, J Rosinski, TF Vogt, ...
Aging (Albany NY) 8 (7), 1485, 2016
2192016
Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease
SDJ Plotkin JL, Day M, Peterson JD, Xie Z, Kress GJ, Rafalovich I ...
Neuron 83 (1), 178-88, 2014
2182014
Resistance to selective BRAF inhibition can be mediated by modest upstream pathway activation
F Su, WD Bradley, Q Wang, H Yang, L Xu, B Higgins, K Kolinsky, ...
Cancer research 72 (4), 969-978, 2012
2122012
Microarray-based identification of differentially expressed growth-and metastasis-associated genes in pancreatic cancer
H Friess, J Ding, J Kleeff, L Fenkell, JA Rosinski, A Guweidhi, ...
Cellular and Molecular Life Sciences CMLS 60, 1180-1199, 2003
1742003
Cascades of transcriptional induction during dendritic cell maturation revealed by genome‐wide expression analysis
Ö Türeci, H Bian, FO Nestle, L Raddrizzani, JA Rosinski, A Tassis, ...
The FASEB journal 17 (8), 836-847, 2003
1072003
Phosphodiesterase 10A inhibition improves cortico-basal ganglia function in Huntington’s disease models
V Beaumont, S Zhong, H Lin, WJ Xu, A Bradaia, E Steidl, M Gleyzes, ...
Neuron 92 (6), 1220-1237, 2016
1022016
Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease
BGP Mielcarek M, Inuabasi L, Bondulich MK, Muller T, Osborne GF, Franklin SA ...
PLoS Genetics 10 (8), 2014
912014
The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle
X Wu, J Wang, X Cui, L Maianu, B Rhees, J Rosinski, WV So, SM Willi, ...
Endocrine 31, 5-17, 2007
882007
Molecular evolution of helix–turn–helix proteins
JA Rosinski, WR Atchley
Journal of molecular evolution 49, 301-309, 1999
721999
Transcriptional regulatory networks underlying gene expression changes in Huntington's disease
SA Ament, JR Pearl, JP Cantle, RM Bragg, PJ Skene, SR Coffey, ...
Molecular systems biology 14 (3), e7435, 2018
672018
Large-scale phenome analysis defines a behavioral signature for Huntington's disease genotype in mice
V Alexandrov, D Brunner, LB Menalled, A Kudwa, J Watson-Johnson, ...
Nature biotechnology 34 (8), 838-844, 2016
572016
DNA methylation study of Huntington’s disease and motor progression in patients and in animal models
AT Lu, P Narayan, MJ Grant, P Langfelder, N Wang, S Kwak, H Wilkinson, ...
Nature communications 11 (1), 4529, 2020
542020
MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice
P Langfelder, F Gao, N Wang, D Howland, S Kwak, TF Vogt, JS Aaronson, ...
PloS one 13 (1), e0190550, 2018
492018
RG7212 anti-TWEAK mAb inhibits tumor growth through inhibition of tumor cell proliferation and survival signaling and by enhancing the host antitumor immune response
X Yin, L Luistro, H Zhong, M Smith, T Nevins, K Schostack, H Hilton, ...
Clinical Cancer Research 19 (20), 5686-5698, 2013
392013
Single Nucelotide Polymorphism (SNP)
M Faham, S Germer, HB Jones, D Lagarde, ML Martin, ME Moorhead, ...
US Patent App. 11/792,772, 2009
332009
Myostatin inhibition prevents skeletal muscle pathophysiology in Huntington’s disease mice
MK Bondulich, N Jolinon, GF Osborne, EJ Smith, I Rattray, A Neueder, ...
Scientific reports 7 (1), 14275, 2017
322017
Preclinical biomarkers for a cyclin-dependent kinase inhibitor translate to candidate pharmacodynamic biomarkers in phase I patients
W Berkofsky-Fessler, TQ Nguyen, P Delmar, J Molnos, C Kanwal, ...
Molecular cancer therapeutics 8 (9), 2517-2525, 2009
252009
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