| Multiscale Agent-Based and Hybrid Modeling of the Tumor Immune Microenvironment KA Norton, C Gong, S Jamalian, AS Popel Processes 7 (1), 37, 2019 | 142 | 2019 |
| A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition C Gong, O Milberg, B Wang, P Vicini, R Narwal, L Roskos, AS Popel Journal of The Royal Society Interface 14 (134), 20170320, 2017 | 139 | 2017 |
| A QSP Model for Predicting Clinical Responses to Monotherapy, Combination and Sequential Therapy Following CTLA-4, PD-1, and PD-L1 Checkpoint Blockade O Milberg, C Gong, M Jafarnejad, IH Bartelink, B Wang, P Vicini, R Narwal, ... Scientific Reports 9 (1), 1-17, 2019 | 75 | 2019 |
| Predicting lymph node output efficiency using systems biology C Gong, JT Mattila, M Miller, JAL Flynn, JJ Linderman, D Kirschner Journal of theoretical biology 335, 169-184, 2013 | 58 | 2013 |
| A Computational Model of Neoadjuvant PD-1 Inhibition in Non-Small Cell Lung Cancer M Jafarnejad, C Gong, E Gabrielson, IH Bartelink, P Vicini, B Wang, ... The AAPS Journal 21 (5), 79, 2019 | 57 | 2019 |
| Digital pathology analysis quantifies spatial heterogeneity of CD3, CD4, CD8, CD20, and FoxP3 immune markers in triple-negative breast cancer H Mi, C Gong, J Sulam, EJ Fertig, AS Szalay, EM Jaffee, V Stearns, ... Frontiers in Physiology 11, 1325, 2020 | 50 | 2020 |
| Harnessing the heterogeneity of T cell differentiation fate to fine-tune generation of effector and memory T cells C Gong, JJ Linderman, D Kirschner Frontiers in immunology 5, 2014 | 48 | 2014 |
| Computational and empirical studies predict Mycobacterium tuberculosis-specific T cells as a biomarker for infection outcome S Marino, HP Gideon, C Gong, S Mankad, JT McCrone, PL Lin, ... PLoS computational biology 12 (4), e1004804, 2016 | 40 | 2016 |
| Quantitative Characterization of CD8+ T Cell Clustering and Spatial Heterogeneity in Solid Tumors C Gong, RA Anders, Q Zhu, JM Taube, B Green, W Cheng, IH Bartelink, ... Frontiers in oncology 8, 2018 | 39 | 2018 |
| A multi-scale approach to designing therapeutics for tuberculosis JJ Linderman, NA Cilfone, E Pienaar, C Gong, DE Kirschner Integrative Biology 7 (5), 591-609, 2015 | 34 | 2015 |
| A Spatial Quantitative Systems Pharmacology Platform spQSP-IO for Simulations of Tumor—Immune Interactions and Effects of Checkpoint Inhibitor Immunotherapy C Gong, A Ruiz-Martinez, H Kimko, AS Popel Cancers 13 (15), 3751, 2021 | 22 | 2021 |
| Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model A Ruiz-Martinez, C Gong, H Wang, RJ Sové, H Mi, H Kimko, AS Popel PLoS computational biology 18 (7), e1010254, 2022 | 21 | 2022 |
| Integrating single cell sequencing with a spatial quantitative systems pharmacology model spQSP for personalized prediction of triple-negative breast cancer immunotherapy response S Zhang, C Gong, A Ruiz-Martinez, H Wang, E Davis-Marcisak, ... ImmunoInformatics, 100002, 2021 | 21 | 2021 |
| A population model capturing dynamics of tuberculosis granulomas predicts host infection outcomes C Gong, JJ Linderman, D Kirschner Mathematical biosciences and engineering: MBE 12 (3), 625, 2015 | 18 | 2015 |
| Strategic Priming with Multiple Antigens Can Yield Memory Cell Phenotypes Optimized for Infection with Mycobacterium tuberculosis: a Computational Study C Ziraldo, C Gong, D Kirschner, JJ Linderman Frontiers in Microbiology 6, 1477, 2015 | 14 | 2015 |
| Quantifying Intratumoral Heterogeneity and Immunoarchitecture Generated In-Silico by a Spatial Quantitative Systems Pharmacology Model M Nikfar, H Mi, C Gong, H Kimko, AS Popel Cancers 15 (10), 2750, 2023 | 4 | 2023 |
| Systems pharmacology to predict cellular biomarkers and optimize mono-and combination-therapy regimens: Focusing on immune checkpoint targets PD-1, PD-L1 and CTLA-4 O Milberg, C Gong, B Wang, P Vicini, R Narwal, L Roskos, A Popel Cancer Research 77 (13 Supplement), 4531-4531, 2017 | 2 | 2017 |
| A multiscale computational model for spatio-temporal tumor immune response C Gong, O Milberg, B Wang, P Vicini, R Narwal, L Roskos, AS Popel Cancer Research 77 (13 Supplement), 975-975, 2017 | 1 | 2017 |
Aleksander S. PopelProfessor of Biomedical Engineering, Johns Hopkins University, School of MedicineVerified email at jhu.edu
